Impedance-pH monitoring is a technique used in the diagnosis of gastroesophageal reflux disease.[1]
Patients with ongoing symptoms while on PPI therapy are commonly diagnosed with impedance-pH monitoring while continuing their medications. The impedance-pH monitoring diagnostic test determines the frequency of reflux episodes and the time relationship of reflux episodes and symptoms. The impedance-pH monitoring test determines if the patient's symptoms are related to acid reflux, related to nonacid reflux, or not related to reflux of any type. A positive GERD diagnosis is made if acid or nonacid reflux precedes symptoms in a statistically meaningful manner. Patients with a positive impedance-pH monitoring test may benefit from acid-reduction therapy such as fundoplication surgery or endoscopic fundoplication techniques.